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New combo aims to shield bone marrow in tough breast cancer

NCT ID NCT07255612

First seen Jan 05, 2026 · Last updated Jun 19, 2026 · Updated 28 times

Summary

This phase 2 trial tests whether adding trilaciclib to the chemotherapy drug eribulin can protect bone marrow in people with advanced triple-negative breast cancer who have already tried at least two prior chemotherapies. The study will enroll 29 participants and measure how often severe low white blood cell counts occur. The goal is to reduce infections and other side effects from chemo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510000, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

trilaciclib and eribulin

What this could lead to

If successful, this could offer a way to reduce severe side effects from chemotherapy, allowing patients to complete treatment with less bone marrow damage.

What could go wrong

This is a small, early-phase study with only 29 participants, so results may not apply broadly. The combination may not work as hoped or could cause unexpected side effects.

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.