Could a Copper-Binding drug ease thickened heart muscles?
NCT ID NCT04706429
First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 30 times
Summary
This study tested whether the drug trientine can reduce heart muscle thickening and improve exercise ability in people with hypertrophic cardiomyopathy, a condition where the heart muscle is abnormally thick. 154 adults took either trientine or a placebo for 12 months. The goal was to see if the drug could improve heart function and reduce abnormal rhythms, while also understanding how it works.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Liverpool Heart and Chester Hospital NHS Foundation Trust
Liverpool, L14 3PE, United Kingdom
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Manchester University NHS Foundation Trust
Manchester, M23 9LT, United Kingdom
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NHS Grampian
Aberdeen, AB25 2ZN, United Kingdom
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Northumbria Healthcare NHS Foundation Trust
North Shields, NE29 8NH, United Kingdom
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Oxford University Hospitals NHS Foundation Trust
Oxford, OX3 9DU, United Kingdom
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Royal Brompton and Harefield NHS Foundation Trust
London, SW3 6NP, United Kingdom
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University Hospitals of Leicester NHS Foundation Trust
Leicester, LE3 9QP, United Kingdom
Conditions
Explore the condition pages connected to this study.