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New drug triapine tested in uterine cancer before surgery

NCT ID NCT04494113

First seen Jan 08, 2026 · Last updated Apr 29, 2026 · Updated 22 times

Summary

This early-phase trial studies how the drug triapine affects uterine serous cancer cells in 12 women scheduled for hysterectomy. Participants receive one dose of triapine before surgery, and researchers compare tumor samples taken before and after the drug to see if it slows cancer growth. The goal is to gather information, not to provide a cure or long-term treatment.

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Contacts and locations

Locations

  • Johns Hopkins University/Sidney Kimmel Cancer Center

    Baltimore, Maryland, 21287, United States

  • Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania, 19107, United States

  • UM Sylvester Comprehensive Cancer Center at Coral Gables

    Coral Gables, Florida, 33146, United States

  • UM Sylvester Comprehensive Cancer Center at Deerfield Beach

    Deerfield Beach, Florida, 33442, United States

  • UM Sylvester Comprehensive Cancer Center at Plantation

    Plantation, Florida, 33324, United States

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    Miami, Florida, 33136, United States

  • VCU Massey Comprehensive Cancer Center

    Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.