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Can a cream stop cancer Treatment's ugly side effect?

NCT ID NCT06358677

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tests whether a cream containing tretinoin (a form of vitamin A) can prevent or reduce the acne-like rash that often occurs in patients taking certain cancer drugs. About 25 adults with advanced solid tumors will apply the cream to one side of their face and a placebo cream to the other side, without knowing which is which. Researchers will compare the rash severity on both sides over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Huntsman Cancer Institute at University of Utah

    RECRUITING

    Salt Lake City, Utah, 84112, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

topical tretinoin

What this could lead to

If it works, this could offer a simple way to manage a common and uncomfortable side effect of certain cancer treatments.

What could go wrong

This is a small, early-phase trial with only 25 participants, so results may not apply broadly. The treatment is tested only on the face and may cause skin irritation.

Conditions

The condition(s) this trial relates to.

metastatic malignant neoplasm neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.