New drug aims to Re-Sensitize tough cancers to chemotherapy
NCT ID NCT02535312
Summary
This study is testing a new oral drug called TRC102 (methoxyamine) to see if it can make tumor cells more sensitive to standard chemotherapy drugs. It is for adults with advanced solid tumors or mesothelioma that have spread or stopped responding to usual treatments. The goal is to find a safe dose and see if this combination can shrink tumors or slow their growth.
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Contacts and locations
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Locations
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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Keck Medical Center of USC Pasadena
Pasadena, California, 91105, United States
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Los Angeles General Medical Center
Los Angeles, California, 90033, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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UCHealth University of Colorado Hospital
Aurora, Colorado, 80045, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
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University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, 21201, United States
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University of Michigan Rogel Cancer Center
Ann Arbor, Michigan, 48109, United States
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University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232, United States
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University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, 53792, United States
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Vanderbilt Breast Center at One Hundred Oaks
Nashville, Tennessee, 37204, United States
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Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee, 37232, United States
Conditions
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