New study seeks biomarkers to predict lung injury in trauma patients
NCT ID NCT07291908
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how severe inflammation after trauma impacts lung function in 130 intensive care patients. Researchers will measure markers like miRNA-126, IL-6, and blood gases to see if they can predict lung injury. The goal is to find better ways to identify patients at risk for complications like acute respiratory distress syndrome (ARDS).
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify biomarkers that help doctors predict lung complications in trauma patients earlier.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to direct patient benefits, and results may not apply to all trauma patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 130 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients (≥18 years) admitted to the anesthesia intensive care units of Akdeniz University Faculty of Medicine with blunt or penetrating trauma. The population represents early post-traumatic ICU admissions without thoracic injury, pre-existing infection, immunodeficiency, or other conditions that may alter the inflammatory response.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Adults aged 18 years or older. Patients monitored and treated for trauma in the anesthesia intensive care units of Akdeniz University Faculty of Medicine. Exclusion Criteria: Patients younger than 18 years. Patients with concomitant thoracic trauma. Presence of active infection prior to trauma. Patients not admitted to the ICU within the first 24 hours after trauma. Patients who remain in the ICU for less than 72 hours following trauma. Current use of steroids, chemotherapy, or antibiotic therapy prior to ICU admission. Patients with immunodeficiency. Patients who are in shock prior to or during ICU admission.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Akdeniz University Hospital
RECRUITINGAntalya, Ağrı, 04200, Turkey (Türkiye)
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