Zapping the brain while exercising shoulder: new hope for pain relief?
NCT ID NCT05951933
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aimed to see if adding a mild electrical current to the brain (transcranial stimulation) during shoulder strengthening exercises helps people with subacromial pain syndrome more than exercise alone. Participants would have done 8 weeks of shoulder exercises while wearing a helmet that delivered either real or fake stimulation. However, the trial was withdrawn before any participants were enrolled, so no data was collected.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- transcranial electrical stimulation (a-TES)
- What this could lead to
- If it worked, this could point toward a way to boost the effects of physical therapy for shoulder pain using mild brain stimulation.
- What could go wrong
- The trial was withdrawn before enrolling anyone, so no results exist. Even if run, it was a small early study and the added benefit of brain stimulation may be minimal or none.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Expected to start
-
Jan 2023
An estimate. Start dates often move.
- Expected to finish
-
Feb 2025
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Subjects will be evaluated during a first consultation by a physiotherapist with experience in shoulder musculoskeletal pathology, following the algorithm for the diagnosis of shoulder problems, recommended by the British Elbow \& Shoulder Society with the aim of detecting possible "flags red" and as a guide to rule out other shoulder pathologies that do not fit into the SDS. However, other tests will be added to ensure diagnostic accuracy, and these are described below. Inclusion Criteria: 1. Age between 18 and 65 years. 2. Duration of pain greater than or equal to 3 months. 3. Presence of 3 or more of the following positive clinical tests: * painful arc * External rotation test against isometric resistance * Neer's test * Jobe test or empty can test * Hawkins-Kennedy test Exclusion Criteria: 1. Previous shoulder or neck surgery. 2. History of shoulder fracture or dislocation. 3. Medical diagnosis of shoulder osteoarthritis. 4. Adhesive capsulitis 5. Cervicobrachialgia or reproducible shoulder pain with neck movements. 6. Clinical signs of total tear of the rotator cuff. 7. Corticosteroid injection in the previous 6 weeks. 8. Inflammatory disease, autoimmune or rheumatic, systemic (arthritis, lupus, myopathies). 9. Cognitive or behavioral problems that make it impossible to understand and follow the intervention (score less than 24 on the Mini-Mental State Examination Score) (73). 10. Any neurological or neoplastic disease. 11. Also those who present contraindications for transcranial electrical stimulation. For this, the recommendations of the checklist of Thair et al. which includes: * personal and family history of epilepsy * metal implants in the head * implanted medication pump * pacemaker * recurring headaches * skin diseases of the scalp (psoriasis, eczema) * head injuries * serious head surgeries * pregnancy * heart diseases * medications (psychotropics or antihistamines).
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Subacromial pain syndrome are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Valencia
Valencia, Valencia, 46010, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could hidden nerve pain explain some shoulder pain cases?
- Why do some shoulder injections work better? a study looks for clues in pain type
- Can a single 2-Hour online session untangle shoulder pain beliefs?
- Can the room you rehab in change how your shoulder heals?
- Unstable weights may change how athletes with shoulder pain move
- Can tape and buzzes beat shoulder pain? new study hopes to find out