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New trial aims to find best drug to stop bleeding in High-Risk C-Sections

NCT ID NCT07423156

Disease control Sponsor: Allama Iqbal Medical College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two drugs—tranexamic acid and vasopressin—to see which works better at reducing blood loss during planned C-sections in women with placenta previa, a condition where the placenta covers the cervix. 58 women will be randomly assigned to receive one of the drugs. The goal is to find a safer way to prevent severe bleeding and reduce the need for blood transfusions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Tranexamic acid and vasopressin
What this could lead to
If this trial shows one drug is better, it could lead to a standard treatment to reduce dangerous bleeding during C-sections for women with placenta previa.
What could go wrong
This is a small, early-phase trial with only 58 participants, so results may not apply to all patients. Both drugs have risks, and the study hasn't started yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 58 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Women of reproductive age Age 18-45 years Diagnosed placenta previa in current pregnancy Scheduled for elective cesarean section Singleton pregnancy Exclusion Criteria: Emergency cesarean section Platelet or coagulation disorder Use of anti-platelet or anti-coagulant drugs Previous history of postpartum hemorrhage Chronic liver disease Chronic kidney disease Gestational diabetes Pregnancy-related hypertensive disorders \-

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Conditions

The condition(s) this trial relates to.

diabetes insipidus placenta praevia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Placenta previa

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Jinnah Hospital

    Lahore, Punjab Province, +92, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.