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Could a simple drug cut bleeding risk in weight-loss surgery?

NCT ID NCT07754396

Disease control Sponsor: G.Gennimatas General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This study looks at whether giving tranexamic acid during weight-loss (bariatric) surgery can reduce bleeding. Researchers will compare patients who received the drug with those who did not, focusing on drops in hemoglobin levels, need for transfusions, hospital stay length, and blood clot complications. The study includes adults who had bariatric surgery at a single hospital.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
tranexamic acid
What this could lead to
If effective, tranexamic acid could become a standard preventive measure to reduce bleeding complications and transfusions in bariatric surgery.
What could go wrong
This is a retrospective observational study, so it cannot prove cause and effect. There is also a potential risk of blood clots, which the study will monitor.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

140 people

The number who actually took part.

Started

May 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients undergoing bariatric surgery at G. Gennimatas General Hospital between May 1, 2024, and April 30, 2026. Participants will be identified retrospectively from hospital medical records.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults (≥18 years of age). * Patients who underwent bariatric surgery at G. Gennimatas General Hospital between May 1, 2024, and April 30, 2026. * Availability of complete perioperative and postoperative medical records. Exclusion Criteria: * Known thrombophilia. * Coagulation disorders. * Chronic anticoagulant or antiplatelet therapy. * Previous pulmonary embolism. * Coronary artery disease. * Chronic kidney disease. * Known hypersensitivity to tranexamic acid.

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Conditions

The condition(s) this trial relates to.

Hemorrhage morbid obesity Obesity obesity disorder Postoperative Hemorrhage Thromboembolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Morbid obesity Obesity Perioperative hemorrhage Postoperative hemorrhage Tranexamic acid

Contacts and locations

Locations

  • General Hospital of Athens G. Gennimatas

    Athens, Greece

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