Could a slower dose ramp-up tame chemo pill side effects?
NCT ID NCT06001762
First seen Jan 17, 2026 · Last updated May 24, 2026 · Updated 19 times
Summary
This study tests whether starting abemaciclib at a lower dose and gradually increasing it causes fewer side effects than the standard fixed dose. About 90 adults with early-stage, hormone receptor-positive breast cancer will take part. The goal is to see if this approach helps people stay on treatment longer with less discomfort.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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Boston Medical Center
Boston, Massachusetts, 02118, United States
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Dana-Farber Cancer Insitute at Londonderry Hospital
Londonderry, New Hampshire, 03053, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Dana-Farber Cancer Institute at Foxborough
Foxborough, Massachusetts, 02035, United States
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Dana-Farber Cancer Institute at Merrimack Valley
Methuen, Massachusetts, 01844, United States
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Dana-Farber Cancer Institute at Milford
Milford, Massachusetts, 01757, United States
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Dana-Farber Cancer Institute at South Shore
South Weymouth, Massachusetts, 02190, United States
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Dana-Farber Cancer Institute at Steward St. Elizabeth's
Brighton, Massachusetts, 02135, United States
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Eastern Maine Medical Center (Northern Light)
Brewer, Maine, 04412, United States
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New England Cancer Specialists
Scarborough, Maine, 04074, United States
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Stamford Hospital
Stamford, Connecticut, 06904, United States
Conditions
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