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Massive ethiopian trial tests hygiene vs. antibiotics for blinding eye disease

NCT ID NCT02754583

Knowledge-focused Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This large study in rural Ethiopia looked at whether providing clean water, sanitation, and face-washing education can reduce trachoma infections in communities that have already received many rounds of antibiotics. Over 47,000 people from 40 communities took part. The goal is to find the best, most cost-effective way to control this blinding eye disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

47,605 people

The number who actually took part.

Started

Dec 2015

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

1 day to 120 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Community Level * Inclusion Criteria * Community in a school district that is within the study area of WagHimra * Area within each school district with a site identified for water point construction * At least 5 rounds of mass azithromycin distributions had been performed within community * Exclusion Criteria: * School districts that are too difficult to reach (more than a 1-day of travel to access) * School districts in the 2 urban regions of the study area, since urban communities have better access to water and sanitation and have less trachoma * Refusal of village chief Individual Level * Inclusion Criteria: * All residents residing within a 1.5km radius from the most promising potential water point the water point sites within the school district that were identified for the study * Exclusion criteria * Refusal of participant \[or parent/guardian\]

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Conditions

The condition(s) this trial relates to.

trachoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Trachoma

Contacts and locations

Locations

  • The Carter Center Ethiopia

    Addis Ababa, Ethiopia

More trials for these conditions

Other studies related to the condition(s) this trial covers.