Herbal capsule takes on hemorrhoid bleeding in major trial
NCT ID NCT07369635
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a herbal capsule called Trĩ Thiên Dược can stop bleeding from grade II internal hemorrhoids better than a standard drug (diosmin). 172 adults with bleeding hemorrhoids took either the herbal capsule or diosmin for 28 days, then were followed for another week. The goal was to see how quickly bleeding stopped and if symptoms improved.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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172 people
The number who actually took part.
- Started
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Jul 2020
- Finished
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Nov 2020
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
\- Inclusion Criteria Patients must meet all of the following criteria to be eligible for the study: * Age 18 to 65 years * Diagnosis of grade II internal hemorrhoids with bleeding, presenting with the following symptoms: Hemorrhoids prolapse with gentle straining and retract spontaneously Presence of blood in stool Congested and/or bleeding hemorrhoids * Having symptoms such as anal pain and anal itching * Willingness to voluntarily participate in the study - Exclusion Criteria Patients meeting any of the following criteria will be excluded from the study: * History of malignancy, including colon cancer and other cancers * Anal polyps and proctitis * Anal fissures with bleeding * Systemic diseases, such as hypertension, liver failure, kidney failure, heart failure, and coagulation disorders. * Other severe acute or chronic illnesses * Mixed hemorrhoids or conditions requiring immediate surgical intervention, such as hematoma, severe bleeding, or hemorrhoidal infarction * Recent use of other hemorrhoid medications (within 7 days prior to study enrollment) * Known allergy to any component of the study medications * Pregnant or lactating women * Patients will be withdrawn from the study if they: Do not adhere to the treatment regimen, including missing medication for more than 3 consecutive days. Or Use other prohibited medications during the study period. Or require routine medical care at the hospital due to non-compliance or other medical reasons.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hanoi Medical University Hospital
Hanoi, 100000, Vietnam