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New drug trial aims to shrink dangerous colon polyps in inherited cancer condition

NCT ID NCT06557733

Summary

This study is testing whether an oral medication called TPST-1495 can reduce the number of polyps in the small intestine and colon of people with Familial Adenomatous Polyposis (FAP), an inherited condition that greatly increases colon cancer risk. Thirty-eight adult participants who have already had their colon removed will take the drug daily for six months while doctors monitor polyp changes through endoscopies. The goal is to see if this treatment can help control polyp growth and potentially lower cancer risk for people living with FAP.

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Contacts and locations

Locations

  • Huntsman Cancer Institute/University of Utah

    Salt Lake City, Utah, 84112, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic Hospital in Arizona

    Phoenix, Arizona, 85054, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • University of Wisconsin Carbone Cancer Center - University Hospital

    Madison, Wisconsin, 53792, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.