Simple change in blood draw technique could slash lab errors in ERs
NCT ID NCT07617103
First seen Jun 27, 2026 · Last updated Aug 28, 2026 · Updated 2 times
Summary
This study tests whether releasing a blood pressure cuff (used as a tourniquet) early during blood collection reduces the rate of hemolysis — when red blood cells burst and ruin the sample. About 792 emergency department patients with non-critical conditions will be randomly assigned to early or late tourniquet release. The goal is to see if a simple timing change can lower the need for repeat blood draws and speed up care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If early tourniquet release reduces hemolysis, it could lead to fewer repeat blood draws and faster diagnoses in emergency rooms.
- What could go wrong
- This is a single-center study testing a procedural change, not a new drug or treatment. The benefit may be small or not apply to other hospitals.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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792 people
The number who actually took part.
- Started
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Jun 2026
- Finished
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Jul 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older * Presenting to the emergency department and triaged as green (semi-urgent) or yellow (urgent) category according to the Emergency Severity Index (ESI) or equivalent institutional triage system * Blood collection (venipuncture) indicated as part of routine clinical care by the attending emergency physician * Ability to provide written informed consent * Accessible peripheral vein suitable for standard venipuncture, most often in the antecubital fossa but at the operator's discretion an alternative peripheral site such as the dorsum of the hand (not requiring intravenous catheter placement for blood collection) Exclusion Criteria: * Blood collection performed via an existing intravenous catheter or central venous access device * Critical illness or hemodynamic instability, including triage category red (resuscitation) at the time of blood collection * Anticoagulant or thrombolytic therapy, or any condition in which collection of a coagulation tube was contraindicated, including a known or suspected coagulation disorder (e.g., hemophilia, thrombocytopenia with platelet count \<50,000/uL) * Known hemolytic disease, a history of active hemolysis, or another hematological condition associated with baseline elevated hemolysis * Red blood cell transfusion within the preceding 24 hours * Pregnancy of any gestational age * Absence of a peripheral vein suitable for standard venipuncture * Local pathology preventing collection from the antecubital fossa: infection, hematoma, burn, active upper extremity injury, lymphedema, an arteriovenous fistula, or the side of a previous mastectomy * Only a single collection tube ordered (the intervention requires at least two tubes, because it is defined by the timing of cuff release relative to tube filling) * Inability to give informed consent, or declining to participate * Previously enrolled in this study (re-enrollment not permitted)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Marmara University Pendik Training and Research Hospital
Pendik, Istanbul, 34899, Turkey (Türkiye)
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