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Simple change in blood draw technique could slash lab errors in ERs

NCT ID NCT07617103

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 28, 2026 · Updated 2 times

Summary

This study tests whether releasing a blood pressure cuff (used as a tourniquet) early during blood collection reduces the rate of hemolysis — when red blood cells burst and ruin the sample. About 792 emergency department patients with non-critical conditions will be randomly assigned to early or late tourniquet release. The goal is to see if a simple timing change can lower the need for repeat blood draws and speed up care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If early tourniquet release reduces hemolysis, it could lead to fewer repeat blood draws and faster diagnoses in emergency rooms.
What could go wrong
This is a single-center study testing a procedural change, not a new drug or treatment. The benefit may be small or not apply to other hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

792 people

The number who actually took part.

Started

Jun 2026

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * Presenting to the emergency department and triaged as green (semi-urgent) or yellow (urgent) category according to the Emergency Severity Index (ESI) or equivalent institutional triage system * Blood collection (venipuncture) indicated as part of routine clinical care by the attending emergency physician * Ability to provide written informed consent * Accessible peripheral vein suitable for standard venipuncture, most often in the antecubital fossa but at the operator's discretion an alternative peripheral site such as the dorsum of the hand (not requiring intravenous catheter placement for blood collection) Exclusion Criteria: * Blood collection performed via an existing intravenous catheter or central venous access device * Critical illness or hemodynamic instability, including triage category red (resuscitation) at the time of blood collection * Anticoagulant or thrombolytic therapy, or any condition in which collection of a coagulation tube was contraindicated, including a known or suspected coagulation disorder (e.g., hemophilia, thrombocytopenia with platelet count \<50,000/uL) * Known hemolytic disease, a history of active hemolysis, or another hematological condition associated with baseline elevated hemolysis * Red blood cell transfusion within the preceding 24 hours * Pregnancy of any gestational age * Absence of a peripheral vein suitable for standard venipuncture * Local pathology preventing collection from the antecubital fossa: infection, hematoma, burn, active upper extremity injury, lymphedema, an arteriovenous fistula, or the side of a previous mastectomy * Only a single collection tube ordered (the intervention requires at least two tubes, because it is defined by the timing of cuff release relative to tube filling) * Inability to give informed consent, or declining to participate * Previously enrolled in this study (re-enrollment not permitted)

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Conditions

The condition(s) this trial relates to.

Emergencies Hemolysis Varicose Ulcer venous insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Marmara University Pendik Training and Research Hospital

    Pendik, Istanbul, 34899, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.