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Brain cancer chemo delivered directly: a safety first

NCT ID NCT03154996

First seen May 08, 2026 · Last updated May 14, 2026 · Updated 2 times

Summary

This early-stage study tested whether it is safe to deliver the chemotherapy drug topotecan directly into the brain over several days for people with recurrent high-grade gliomas, a serious type of brain cancer. Only 5 participants were enrolled. The main goal was to find a dose that causes no more than mild side effects, and researchers also looked for signs that the drug was reaching the tumor and shrinking it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

Conditions

Explore the condition pages connected to this study.