Brain cancer: direct chemo delivery shows early safety promise
NCT ID NCT03154996
First seen May 08, 2026 · Last updated May 08, 2026
Summary
This early-phase study tested whether it is safe to deliver the chemotherapy drug topotecan directly into the brain over several days for people with recurrent high-grade gliomas (aggressive brain tumors). Five adults whose tumors had returned after standard treatments took part. The main goal was to find a dose that does not cause severe side effects, while also checking if the treatment could shrink tumors.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Columbia University Irving Medical Center
New York, New York, 10032, United States
Conditions
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