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Simple wound treatment slashes Post-Surgery complications in breast cancer patients

NCT ID NCT07434453

Disease control Sponsor: Noor ul Ain Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether applying tranexamic acid (TXA) directly into the wound during mastectomy surgery could reduce fluid buildup and infection. 62 women with breast cancer were split into two groups: one received TXA plus a special stitching technique, the other had stitching alone. Results showed that TXA significantly lowered fluid collection and wound infections, suggesting a safe, cheap way to improve recovery after breast cancer surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
tranexamic acid
What this could lead to
If confirmed, this simple, low-cost method could become a standard step in breast cancer surgery to reduce complications and improve healing.
What could go wrong
This was a small, single-center study with 62 patients. Larger trials are needed to confirm the benefits and ensure safety across diverse populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

62 people

The number who actually took part.

Started

Aug 2023

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. all females. 2. Age more than 18 Years Exclusion Criteria: 1. high risk of thromboembolism requiring anti-coagulant in perioperative period 2. known allergy to Tranexamic acid documented in history 3. patients requiring delayed wound closure after MRM 4. wound edge necrosis documented on examination postoperatively 5. preoperative involvement of muscle and bone and less than R0 resection.

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Conditions

The condition(s) this trial relates to.

breast cancer female breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer females

Contacts and locations

Locations

  • king Edward medical university/mayo hospital lahore

    Lahore, Punjab Province, 54000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.