Gum graft recovery boosted by simple steroid cream?
NCT ID NCT07409571
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether applying a topical steroid (triamcinolone acetonide) to the roof of the mouth after gum graft surgery can speed healing, reduce pain, and improve quality of life. About 55 adults needing a gum graft will be randomly assigned to receive either the steroid or a standard collagen membrane. Researchers will check wound healing, scarring, pain, and daily-life impact over 30 days.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 55 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years and older * Patients presenting with insufficient attached gingiva and/or gingival recession requiring free gingival graft surgery * Systemically healthy individuals (ASA I) * Full-mouth plaque score (FMPS) \< 15% and full-mouth bleeding score (FMBS) \< 15% at the time of surgery * Ability and willingness to provide written informed consent and comply with study procedures Exclusion Criteria: * Presence of systemic diseases that may affect wound healing (e.g., diabetes mellitus, immunological disorders) * Use of systemic corticosteroids, immunosuppressive drugs, or anti-inflammatory medications within the last 3 months * Current smokers or tobacco users * Pregnancy or lactation * History of periodontal surgery at the palatal donor site * Presence of active infection, ulceration, or pathological lesions at the palatal donor area * Known allergy or hypersensitivity to corticosteroids, collagen materials, or study-related medications
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kahramanmaraş Sütçü İmam University
RECRUITINGKahramanmaraş, Kahramanmaraş, 46000, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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- Mouthrinse showdown: which rinse heals gum grafts best?
- Sticky bone may boost gum graft success for receding gums
- Could your own blood help you heal faster after gum surgery?