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Can this toothpaste soothe sore gums?

NCT ID NCT07494747

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special toothpaste can improve gum inflammation (gingivitis) in adults. Sixty participants with moderate gum inflammation will use either the test toothpaste or a regular one for 4 weeks. Dentists will check gum health at the start and end to see if the test toothpaste helps reduce redness and swelling better than regular toothpaste.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
gingivitis toothpaste
What this could lead to
If it works, this could offer a simple, at-home way to reduce gum inflammation and improve oral health.
What could go wrong
This is a small, short-term study (60 people, 4 weeks) testing a cosmetic product, so results may not be dramatic or long-lasting. It's not a treatment for severe gum disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Healthy male and female subjects (with no specific repartition) 2. Subjects of Caucasian ethnicity 3. Subjects aged between 18 and 65 years (extremes included) 4. Subjects clinically showing moderate gums inflammation (gingivitis grade II, in particular all gingival scores for the mean should be between 1.75 and 2.3, according to Löe and Silness gingival scoring system), in particular: 1. 40% of the subjects with localized gingivitis (10-30% of evaluated sites with bleeding) 2. 60% of them with generalized gingivitis (\>30% of evaluated sites with bleeding) Repartition to be respected in both study groups. 5. Subjects with dental plaque (total plaque score at inclusion ≥2) 6. Subjects registered with the national health service 7. Subjects certifying the truthfulness of the personal data disclosed to the Principal Investigator or designated personnel 8. Subjects able to understand the language used in the investigation centre and the information given by the Principal Investigator or designated personnel 9. Subjects able to respect the instructions given by the Principal Investigator or designated personnel as well as able to respect the study constraints and specific requirements 10. Subjects who commit not to change their daily routine or lifestyle during the study 11. Subjects on stable pharmacological therapy (except for the pharmacological therapy in the non-inclusion criteria) for at least one month without any changes expected or planned during the study 12. Subjects informed about the test procedures who have signed a consent form and privacy agreement Exclusion Criteria: 1. Subjects who do not meet the inclusion criteria 2. Smokers subjects 3. Subjects planning toothcare during the study period 4. Subjects using dental apparatus or using dental prosthesis, with generalized tooth recession, with presence of caries, with dental abscess or signs of periodontitis (periodontal probing depth \>3mm) or active periodontitis 5. Subjects using other dental hygiene products than provided (e.g. dental floss, interdental brushes, mouthwash, etc) during the study period 6. Subjects with any acute, chronic, or progressive disease or condition that may interfere with the study data or that the Principal Investigator considers dangerous to the subject or incompatible with the requirements of the study 7. Subjects participating or planning to participate in other clinical trials 8. Subjects who participated in a similar study without respecting an adequate washout period (at least one month) 9. Subjects that have food intolerances or food allergies to ingredients of the study product 10. Subjects under pharmacological treatments that are considered incompatible with the study requirement by the Principal Investigator 11. Subjects who are currently using food supplement(s) and/or products with the same activity as the study product, or who haven't observed an adequate washout period (at least one month) 12. Subjects admitted to a health or social facility 13. Subjects planning a hospitalization during the study 14. Subjects not able to be contacted in case of emergency 15. Subjects deprived of freedom by administrative or legal decision or under guardianship 16. Subjects who have or have had a history of alcohol or drug addiction 17. Subjects with eating disorders (i.e. bulimia, psychogenic eating disorders, etc.) 18. Subject breastfeeding, pregnant or not willing to take necessary precautions to avoid pregnancy during the study (for the women of childbearing potential).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CLINICA CIURANA Centre Dental

    RECRUITING

    Castelldefels, Barcelona, 08860, Spain

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