Toothpaste showdown: can it stop the zing?
NCT ID NCT07593755
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a desensitizing toothpaste, used alone or with a mouthwash, can reduce tooth sensitivity in adults. 71 participants used the products daily for 14 days. Researchers measured changes in sensitivity to see if the toothpaste worked better than regular toothpaste.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
71 people
The number who actually took part.
- Started
-
Feb 2025
- Finished
-
Apr 2025
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy female and male participants (no specific gender distributions required) * Aged 18 years or older * Participants presenting dental hyperesthesia with at least two hypersensitive teeth with a verbal rating scale (VRS) score greater than or equal to 1 after tactile stimulation, and a Schiff Cold Air Sensitivity Scale score greater than or equal to 1 at the initial visit (T0). * Participants certifying the truthfulness of the personal data disclosed to the investigator. * Participants able to understand the language used at the investigation centre and comprehend the information provided by the investigator. * Participants able to follow the instructions provided by the investigator and comply with the study requirements and restrictions. * Pharmacological therapy (except for therapies listed under non-inclusion criteria) must have been stable for at least one month, with no changes expected or planned during the study * Commitment by the participants not to change the daily routine or lifestyle during the study. * Participants who have not taken part in any other similar clinical study in the previous six months. * Commitment by the participant not to use other oral hygiene products containing fluoride or ingredients such as hydroxyapatite during the study period. Exclusion Criteria: * Participants currently participating or planning to participate in other clinical trials. * Participants deprived of liberty by administrative or judicial decision or under guardianship. * Participants who cannot be contacted in the event of an emergency. * Participants admitted to a healthcare or social institution. * Participants planning hospitalization during the study period. * Participants who have taken part in a similar study without respecting an adequate washout period (defined as the use of desensitizing agents within the last six months). * Participants under pharmacological treatments that modify the evaluation of dental sensitivity or are incompatible with the requirements of the study. * Participants with a history of active caries within the past 12 months or at risk for developing caries (e.g., multiple dental restorations, crowns with compromised margins) per examiners discretion. * Participants with known allergies or sensitivities to any components of the investigational product. * Women who are breastfeeding, pregnant, or unwilling to take the adequate contraceptive measures to avoid pregnancy during the study (for women of childbearing potential). * Participants with acute, chronic, or progressive pathologies (including diabetes, cardiovascular and metabolic conditions) incompatible with the study requirements. * Any tooth surface adjacent to those surfaces under investigation that in the opinion of the investigator have any other condition that produce symptoms confounding the evaluation of cervical dentin hypersensitivity. * Participants with a medical history or taking medication, or wearing physical items (e.g., orthodontic braces) that could interfere with the study. * Participants with a history of illegal drug use.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Dental sensitivity are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital Odontológico Universidad de Barcelona - Bellvitge
Barcelona, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New dissolvable strips promise fast relief for sensitive teeth
- Which tooth whitening method causes less pain? new study compares
- Laser or glass powder: which eases tooth pain best?
- Can special toothpaste stop the pain of sensitive teeth?
- New varnish showdown: can a fluoride coating soothe sensitive teeth?
- New study tests two ways to soothe sensitive teeth