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New antibiotic paste could replace root canals for Kids' tooth infections

NCT ID NCT06811636

First seen Jan 10, 2026 · Last updated Jun 23, 2026 · Updated 20 times

Summary

This study compares two treatments for infected baby molars in children aged 3 to 8: a less invasive method using a triple antibiotic paste (lesion sterilization and tissue repair) versus a standard root canal with a calcium hydroxide-iodoform paste. The goal is to see which approach better relieves pain, swelling, and infection, and leads to healthier teeth on X-rays. The trial involves 74 children and is currently active but not recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Canakkale Onsekiz Mart University

    Çanakkale, Kepez, 17100, Turkey (Türkiye)

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

triple antibiotic paste (lesion sterilization and tissue repair) and calcium hydroxide-iodoform paste (root canal treatment)

What this could lead to

If successful, the antibiotic paste method could offer a simpler, less invasive alternative to standard root canals for treating infected baby teeth in children.

What could go wrong

This is a small, early-stage study with only 74 children, so results may not apply to everyone. The antibiotic paste might not work as well as the standard treatment, and there is a risk of allergic reactions or treatment failure.

Conditions

The condition(s) this trial relates to.

dental abscess dental pulp necrosis pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.