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Your tooth, your graft: new study tests natural bone preservation

NCT ID NCT06429540

Disease control Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a graft made from a patient's own extracted tooth can preserve the jawbone as well as a standard animal-based bone substitute. 26 adults with non-restorable front teeth received either the tooth graft or the standard material. After 6 months, the researchers measured bone width and height changes using CT scans to see which method worked better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Partially Demineralized Dentin Block (made from the patient's own tooth)
What this could lead to
If it works, this could offer a cheaper, natural alternative to animal-based bone grafts for preserving jawbone after tooth removal.
What could go wrong
This is a small, early study with only 26 participants. The dentin graft is experimental and may not preserve bone as well as standard materials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

26 people

The number who actually took part.

Started

Mar 2024

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with non-restorable teeth and Type II extraction socket in the esthetic zone * Healthy patients with adequate oral hygiene (bleeding on probing ≤20%; Plaque index ≤20%). * Systemically healthy. Exclusion Criteria: * Heavy smokers (more than 10 cigarettes per day or an electronic cigarette dose of \>6 mg/ml of nicotine). * Patients reporting systemic conditions that may compromise healing or bone metabolism (eg: diabetes). * Patients with poor oral hygiene (bleeding on probing \>20%; Plaque index \>20%) * The presence of acute periapical infection. * The presence of severe periodontal destruction.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Socket preservation

Contacts and locations

Locations

  • Faculty of dentistry Cairo University

    Cairo, Elmanil, Egypt

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