Can a simple flowchart improve Alzheimer's blood test conversations?
NCT ID NCT07812337
First seen Sep 10, 2026 · Last updated Sep 11, 2026 · Updated 1 time
Summary
Researchers at the University of Wisconsin, Madison are testing a decision-support tool that helps primary care providers talk with patients about blood biomarker testing for Alzheimer's disease. The tool is a flowchart that gives clear information about the Phospho-Tau blood test and guides discussions about memory problems. The study compares clinical encounters where providers use the tool with those where they do not, to see if the tool improves shared decision-making. About 70 people, including primary care providers and older adults with memory concerns, will take part.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a shared decision-making support tool for discussing Alzheimer's blood biomarker testing
- What this could lead to
- If the tool works, it could help primary care providers and patients have clearer, more informed conversations about Alzheimer's blood tests. That may lead to better decisions about memory evaluations.
- What could go wrong
- This is a small pilot study with 70 participants, so results may not apply widely. The tool might not improve decision-making or could be hard for busy clinics to use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Simulation 1 and Simulation 2: PCPs with experience and interest in cognitive diagnosis. * Simulation 2: community dwelling older adults age 50 or older are eligible. Exclusion Criteria (PCP): none Participant Exclusion Criteria: * Not fluent in English * age \<50 years * pre-existing diagnosis of cognitive impairment * having an activated medical decision-make r or not living independently in the community. There will be no exclusion based upon sex/gender, race, or ethnicity.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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School of Medicine and Public Health, University of Wisconsin
Madison, Wisconsin, 53705, United States
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Other studies related to the condition(s) this trial covers.