Can a simple message help smokers use fewer cigarettes? new study aims to find out.
NCT ID NCT06787937
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether giving smokers very low nicotine cigarettes (VLNCs) along with educational messages about them leads to smoking less, compared to just using VLNCs alone. About 1,230 adult smokers will be split into two groups and followed for several weeks. The goal is to see if the messages make a real difference in how many cigarettes people smoke each day.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Very low nicotine cigarettes (VLNCs) and behavioral messaging
- What this could lead to
- If it works, this could show that combining educational messages with reduced-nicotine cigarettes helps people smoke less, pointing toward better public health campaigns.
- What could go wrong
- This is a behavioral study, not a treatment trial. Results may not apply to all smokers, and the effect of messages alone may be small or short-lived.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,230 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Jan 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 21+ years * Current smoker (self-report as having smoked 100 cigarettes in their lifetime and currently smoking on 27+ days out of past 30, expired breath carbon monoxide \[CO\] ≥6ppm to assess regular smoking) * Can speak, read, and write in English * Available for period of study * Willing to try novel research cigarettes Exclusion Criteria: * Pregnancy or lactation * Member of the same household as a study subject * Unwilling to use research cigarettes as part of the trial
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
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Georgia State university
RECRUITINGAtlanta, Georgia, 30303, United States
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