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Tobacco flavor study seeks to understand Vapers' sense of smell and taste

NCT ID NCT04358315

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how well people can identify and rate different flavors and smells in e-liquids. Researchers compared the abilities of everyday vapers and trained experts to detect flavors, find the lowest detectable levels, and pick out the main flavor in mixtures. The goal was to learn more about how consumers perceive tobacco product flavors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

29 people

The number who actually took part.

Started

Apr 2023

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Current daily vapers and nonusers in the greater Buffalo and Rochester areas

Ages

21 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * CONSUMER USER: Current daily vapers of products containing nicotine * CONSUMER USER: No concurrent use of other tobacco products * CONSUMER USER: General good health * CONSUMER USER: No allergies * CONSUMER USER: No self-reported taste or smell deficits * CONSUMER USER: Not pregnant or lactating * CONSUMER USER: No medications known to interfere with taste/smell * CONSUMER USER: Passing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests * CONSUMER USER: No positive diagnosis of COVID-19 within 30 days * CONSUMER NONUSER: No use of tobacco or nicotine products in the last year * CONSUMER NONUSER: General good health * CONSUMER NONUSER: No allergies * CONSUMER NONUSER: No self-reported taste or smell deficits * CONSUMER NONUSER: Not pregnant or lactating * CONSUMER NONUSER: No medications known to interfere with taste/smell * CONSUMER NONUSER: Passing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests * CONSUMER NONUSER: No positive diagnosis of COVID-19 within 30 days Exclusion Criteria: * CONSUMER USER: Outside age range * CONSUMER USER: Not current daily vapers * CONSUMER USER: Concurrent use of other tobacco products * CONSUMER USER: Fair or poor general health * CONSUMER USER: Allergies * CONSUMER USER: Self-reported taste or smell deficits * CONSUMER USER: Pregnant or lactating * CONSUMER USER: Medications known to interfere with taste/smell * CONSUMER USER: Failing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests * CONSUMER USER: Positive diagnosis of COVID-19 within 30 days * CONSUMER NONUSER: Outside age range * CONSUMER NONUSER: Use of tobacco or nicotine products in the last year * CONSUMER NONUSER: Fair or poor general health * CONSUMER NONUSER: Allergies * CONSUMER NONUSER: Self-reported taste or smell deficits * CONSUMER NONUSER: Pregnant or lactating * CONSUMER NONUSER: Medications known to interfere with taste/smell * CONSUMER NONUSER: Failing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests * CONSUMER NONUSER: Positive diagnosis of COVID-19 within 30 days

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

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