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New combo tackles advanced melanoma from two angles

NCT ID NCT03293784

First seen Apr 04, 2026 · Last updated May 19, 2026 · Updated 5 times

Summary

This early-phase study tested whether adding a TNF-blocker (infliximab or certolizumab) to standard immunotherapy (nivolumab + ipilimumab) is safe for people with advanced melanoma that has spread or cannot be removed. 33 adults aged 18–70 took part. The main goal was to find the best dose and check for serious side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Institut Claudius Regaud IUCT-ONCOPOLE

    Toulouse, 31059, France

Conditions

Explore the condition pages connected to this study.