Scientists zap brains to unlock secrets of vision
NCT ID NCT01617408
First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 5 times
Summary
This study aims to understand how the brain processes what we see, like faces, tools, and scenes. Healthy volunteers aged 18-50 will perform visual tasks while having brain scans (MRI) and receiving mild brain stimulation (TMS or tES). The goal is to map which brain areas handle different aspects of vision, not to test a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 665 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2013
- Lead sponsor
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A government research agency
The lead sponsor is the US National Institutes of Health.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Neurologically normal subjects aged between 18 and 50 years old.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
* INCLUSION CRITERIA: Healthy Ages 18-50 years (inclusive) Able to read and write in English to guarantee understanding of all written and spoken instructions, which are in English EXCLUSION CRITERIA: Individuals with conditions that could pose a risk relating to the safety of the MRI procedure, the TMS procedure or the combined TBS and fMRI procedure will be excluded from the protocol such as: * Those with ferromagnetic metal in the cranial cavity or eye, e.g. aneurysm clip, implanted neural stimulator, cochlear implant, ocular foreign body. * Those with an abnormality on a structural MRI. * Those with an implanted cardiac pacemaker or auto-defibrillator * Those with an insulin pump. * Those with an irremovable body piercing * Pregnant women * Those with a visual impairment that will prevent them from performing the task * Those without consent capacity will not be enrolled * Those who do not understand the study instructions * Those with a history of neurological problems. Neurological problems include, but are not limited to; family history of epilepsy, history of seizures and recurrent migraines. * Those using medicines that can lower the seizure threshold. These can include but are not limited to; imipramine, amitriptyline, doxepine, nortriptyline, maprotiline, chlorpromazine, clozapine, foscarnet, ganciclovir, ritonavir, amphetamines. * Those with a visual impairment that will prevent them from performing the task * Those who have a significant psychiatric illness or have a history of psychiatric illness. * NIMH staff/employees/family members
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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