Shock and step: new combo therapy aims to get stroke patients moving again
NCT ID NCT07512492
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether combining a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) with balance exercises could improve walking in people who had a stroke. Thirty stroke survivors, aged 50 to 60, participated. Researchers measured changes in their gait and ankle movement to see if the combination therapy helped.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Transcranial Magnetic Stimulation (TMS) device and proprioceptive training exercises
- What this could lead to
- If it works, this could point toward a non-invasive way to improve walking ability in stroke survivors.
- What could go wrong
- This is a small, completed study with only 30 participants, so results may not apply to everyone. TMS effects can be mild and vary from person to person.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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30 people
The number who actually took part.
- Started
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Dec 2024
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Thirty patients with stroke from both sexes. 2\) Age will range from 50 to 60 years old. 3\) Duration of stroke ≥ 6 months. 4\) Spasticity of the lower limb ranges from 1+ to 2 according to modified ashworth scale 5\) The patients able to walk with or without assistive device. 6\) Body mass index is less than 30 kg/m2. 7\) Patients with sufficient cognitive abilities that enables them to understand and follow instructions (Mini-Mental State Examination scale \>24). Exclusion Criteria: 1. Previous history of any other neurological disorder 2. Recurrent stroke. 3. Vestibular deficits. 4. Cognitive impairment (a score less than 24 according to mini mental state examination). 5- Cardiac pacemaker 6- Metallic Implants. 7- Aphasia, deafness or blindness 7\. Deformities or contractures of the lower limbs
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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the Qasr El Eyni Hospitals and Private clinics.
Cairo, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Robot could let stroke patients rehab their hands at home without a therapist
- Moving patterns may help stroke survivors read faster
- Vibrating wearables put stroke walking to the test
- Robot plus electrical stimulation aims to rebuild arm movement after stroke
- Can a checklist and heart monitor stop repeat strokes?
- Heart hole or stroke trigger? global registry tracks who gets closure and what happens next