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Brain zaps for teen PTSD? small study tests TMS after therapy fails

NCT ID NCT07401225

Symptom relief Sponsor: The University of Texas Health Science Center at San Antonio Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This study tests whether transcranial magnetic stimulation (TMS) can help teens aged 12-20 who still have PTSD symptoms after finishing trauma-focused therapy. About 20 participants will receive 10 TMS sessions over a month. The goal is to see if TMS is safe and acceptable, and to gather early data for larger future studies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial magnetic stimulation (TMS) device
What this could lead to
If it works, this could point toward a new treatment option for teens with PTSD that doesn't go away after talk therapy.
What could go wrong
This is a very small early study with only 20 participants, so results may not apply to everyone. It focuses on safety and feasibility, not yet on proving effectiveness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

12 to 20 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Males and females; Age 12-20 2. Have previously completed at least 9 sessions of trauma-focused therapy in our clinical trial or in the community 3. Have current self-reported symptom score of 20 or greater on the UCLA PTSD Reaction index 4. Willing to attend 10 TMS treatment sessions within a 30-day period 5. Fluent in English Exclusion Criteria: 1. History of seizures 2. History of head injury with loss of consciousness and concussive sequelae 3. Brain abnormality such as tumor or other observable abnormality 4. Currently receiving psychotherapy or TMS treatment 5. Currently pregnant 6. MRI contraindications (metal in body, orthodontic braces) 7. Diagnosis of bipolar 1 or a psychotic disorder

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post traumatic stress disorder PTSD Posttraumatic stress disorder in adolescents

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • UT Health Department of Psychiatry

    RECRUITING

    San Antonio, Texas, 78229, United States

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