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Brain zaps for war trauma? new TMS study hints at faster PTSD relief

NCT ID NCT06587659

Symptom relief Sponsor: The University of Texas Health Science Center at San Antonio Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new way to treat post-traumatic stress disorder (PTSD) in veterans and active-duty service members. Instead of relying on talk therapy, which can be stressful and has high dropout rates, researchers used a device called transcranial magnetic stimulation (TMS) to stimulate the brain. Seven participants received daily TMS sessions for two weeks. The goal was to see if this standalone treatment could reduce PTSD symptoms, potentially offering a faster and more tolerable option.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Transcranial Magnetic Stimulation (TMS)
What this could lead to
If this works, it could offer a faster, non-invasive treatment option for combat-related PTSD without the need for intensive psychotherapy.
What could go wrong
This is a very small, early-stage trial with only 7 participants. The results may not apply to all PTSD patients, and the long-term benefits are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

7 people

The number who actually took part.

Started

Jan 2025

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. between the ages of 18 and 70 years 2. meet diagnostic criteria for PTSD on the CAPS-5 3. able to attend all clinic appointments 4. fluent in English Exclusion Criteria: 1. a documented diagnostic history of bipolar disorder, schizophrenia or schizoaffective disorder or a psychiatric hospitalization in the last 12 months 2. significant cognitive impairment determined by inability to comprehend screening assessment 3. psychiatric problems and/or high suicide risk warranting immediate intervention, as assessed with the PHQ-9 (Item #9) 4. currently meeting a psychiatric diagnosis of alcohol and/or substance abuse that would prevent the participant from engaging in therapy 5. any history or signs of serious medical or neurological illness including seizure disorders 6. history of traumatic brain injury (TBI) with loss of consciousness for 20 minutes or more 7. females will be excluded if they are pregnant 8. any history or signs of metal objects deemed unsafe for MRI or that may adversely affect image quality of the brain region (e.g. surgical clips, cardiac pacemakers, metal implants, etc.) in the body at the time of screening.

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stress disorders, post-traumatic

Contacts and locations

Locations

  • Research Imaging Institute

    San Antoio, Texas, 78229, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.