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Zapping the brain to unlock reward learning secrets

NCT ID NCT06323057

Knowledge-focused Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 04, 2026 · Updated 3 times

Summary

This study tests whether a non-invasive brain stimulation technique called TMS can alter brain signals related to reward processing. Researchers will apply TMS to the frontal cortex of 28 healthy adults while they perform decision-making tasks. The goal is to see if TMS can increase or decrease a specific brain wave linked to how we respond to rewards, and whether this affects learning and choices.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Transcranial magnetic stimulation (TMS)
What this could lead to
If successful, this could help researchers understand how to influence reward-related brain activity, potentially informing future treatments for conditions like addiction or depression.
What could go wrong
This is a small, early-stage study in healthy volunteers, so results may not apply to clinical populations. TMS may cause mild discomfort or headache, but serious risks are rare.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

36 people

The number who actually took part.

Started

Feb 2024

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Be between the ages of 18 and 55 years old. * Be in stable mental and physical health. * If female, test non-pregnant. * Be willing to provide informed consent. * Be able to comply with protocol requirements and likely to complete all study procedures. Exclusion Criteria: * Contraindication to rTMS (history of neurological disorder or seizure, increased intracranial pressure, brain surgery, or head trauma with loss of consciousness for \> 15 minutes, implanted electronic device, metal in the head, or pregnancy). * History of autoimmune, endocrine, viral, or vascular disorder affecting the brain. * Life time history of mental disorders such as: Bipolar Affective disorder (BPAD), Schizophrenia, Post-traumatic Stress disorder (PTSD) or Dementia or Major Depression. * uninterruptable central nervous system medication

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Conditions

The condition(s) this trial relates to.

Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Behavior

Contacts and locations

Locations

  • Rutgers University - Newark

    Newark, New Jersey, 07102, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.