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New drug targets tough cancers in early trial

NCT ID NCT07204340

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 41 times

Summary

This early-phase study tests a new drug called TLN-372 in people with advanced solid tumors that have a specific genetic change called a KRAS mutation. The main goals are to check the drug's safety and how well it fights tumors, both alone and with other cancer drugs. About 240 adults with measurable disease and good organ function are being recruited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215-5450, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Universitary Vall d'Hebron

    RECRUITING

    Barcelona, 08035, Spain

    Contact

  • Linear Clinical Research

    RECRUITING

    Perth, Western Australia, 6009, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10021-3402, United States

    Contact Phone: •••-•••-••••

  • Peter MacCallum Cancer Centre

    RECRUITING

    Melbourne, Victoria, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, M5G 1X6, Canada

    Contact

  • START Madrid_Hospital Universitario HM Sanchinarro_CIOCC

    RECRUITING

    Madrid, 28050, Spain

    Contact

  • START Midwest

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sarah Cannon Research Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact Email: •••••@•••••

  • Washington University Medical Campus

    RECRUITING

    St Louis, Missouri, 63108, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.