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New drug candidate TJ101 enters first human trials for tough cancers

NCT ID NCT07181473

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 26 times

Summary

This early-phase study tests TJ101, an experimental antibody-drug conjugate, in 200 adults with advanced solid tumors (lung, prostate, esophageal, and others) who have no standard options left. The main goals are to find a safe dose and check for early signs of tumor shrinkage. Participants receive intravenous infusions and are closely monitored for side effects and treatment response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Florida Cancer Specialists & Research Institute

    RECRUITING

    Orlando, Florida, 32827, United States

    Contact Phone: •••-•••-••••

  • Henan Cancer Hospital

    NOT_YET_RECRUITING

    Zhengzhou, Henan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Oncology Consultants

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sarah Cannon Research Institute (SCRI)

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact Phone: •••-•••-••••

  • Shanghai East Hospital

    RECRUITING

    Shanghai, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sir Run Run Shaw Hospital

    NOT_YET_RECRUITING

    Hangzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Union Hospital of Tongji Medical College

    NOT_YET_RECRUITING

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.