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Brain tumor tissue bank could unlock new drug targets

NCT ID NCT04852354

Knowledge-focused Sponsor: Weill Medical College of Cornell University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study collects leftover brain and spinal cord tumor tissue from 500 patients during surgery or autopsy. Researchers will use the tissue to create cell lines and models to test how different drugs work. The goal is to better understand these tumors and find new ways to treat them.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could lead to better treatments and new therapy targets for central nervous system tumors.
What could go wrong
This is an early-stage tissue collection study, not a treatment trial. Results may not directly benefit participants or lead to immediate therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2020

Expected to finish

Jul 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with a central nervous system tumors. Parents of patients with CNS tumors.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for Tumor patients undergoing neurosurgery (cohort 1) 1. Subject has presented with a suspected/confirmed neoplastic CNS lesion and is undergoing a neurosurgical procedure in which CNS tissue and/or tumors associated with this tissue will be removed. 2. There must be tissue available in excess of that required by neuropathology for diagnostic purposes. 3. Subject of all ages included. 4. Subjects who are pregnant can be included. 5. Subjects who are neonates (0-4 weeks) can be included. Inclusion Criteria for Non-tumor patients undergoing neurosurgery (cohort 2) 1. Subject is between 4 weeks and 21 years of age and is undergoing a neurosurgical procedure at WCMC. 2. Subject does not have a CNS tumor diagnosis. 3. Subject should not be pregnant at the time of enrollment. Inclusion Criteria for Autopsy tumor tissue donation (cohort 3) 1. Subject of all ages included 2. Subject has been diagnosed with a neoplastic CNS lesion at the time of passing. 3. Subjects who are pregnant can be included. 4. Subjects who are neonates (0-4 weeks) can be included. Inclusion Criteria for parent of tumor patients 1. Subject is the biological parent of a patient undergoing/ who underwent a neurosurgical procedure in which CNS tissue and/or tumors associated with this tissue will be/ was removed. 2. Subject is the biological parent of patient enrolled in cohort 1. 3. Subject is not pregnant at the time of enrollment.

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Conditions

The condition(s) this trial relates to.

central nervous system cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Central nervous system tumor

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Weill Cornell Medicine

    RECRUITING

    New York, New York, 10021, United States

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