New cell therapy targets stubborn leukemia in kids
NCT ID NCT03876769
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 18 times
Summary
This study tests a treatment called tisagenlecleucel for children and young adults (ages 1-25) with a high-risk type of B-cell leukemia. Participants have cancer cells still present after initial chemotherapy. The treatment uses the patient's own immune cells, modified to attack the cancer. The goal is to see if this therapy can keep the cancer away without needing a stem cell transplant.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children s Hospital of Alabama
Birmingham, Alabama, 35233, United States
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Children s Mercy Hospital
Kansas City, Missouri, 64108, United States
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Childrens Healthcare of Atlanta
Atlanta, Georgia, 30342, United States
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Childrens Hospital Colorado
Aurora, Colorado, 80045, United States
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Childrens Hospital Los Angeles
Los Angeles, California, 90027, United States
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Childrens Hospital of Orange County
Orange, California, 92868-3874, United States
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Childrens Hospital of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Childrens National Hospital
Washington D.C., District of Columbia, 20010, United States
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Cinn Children Hosp Medical Center
Cincinnati, Ohio, 45229-3039, United States
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City of Hope National Medical
Duarte, California, 91010, United States
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Columbia University Medical Center
New York, New York, 110032, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Duke University Medical Center
Durham, North Carolina, 27710, United States
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Hackensack Uni Medical Center
Hackensack, New Jersey, 07601, United States
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James Whitcomb Riley Hospital For Children
Indianapolis, Indiana, 46202, United States
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Johns Hopkins All Childrens
St. Petersburg, Florida, 33701, United States
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Johns Hopkins Oncology Center
Baltimore, Maryland, 21231, United States
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Mattel Childrens Hospital UCLA
Los Angeles, California, 90095, United States
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Memorial Sloan Kettering Cancer Ctr
New York, New York, 10065, United States
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Methodist Childrens Hospital
San Antonio, Texas, 78229, United States
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Novartis Investigative Site
Ghent, 9000, Belgium
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Novartis Investigative Site
Calgary, Alberta, T3B 6A8, Canada
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Novartis Investigative Site
Toronto, Ontario, M5G 1X8, Canada
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Novartis Investigative Site
Montreal, Quebec, H3T 1C5, Canada
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Novartis Investigative Site
Copenhagen, DK-2100, Denmark
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Novartis Investigative Site
Paris, 75019, France
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Novartis Investigative Site
Roma, 165, Italy
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Novartis Investigative Site
Utrecht, 3584 CS, Netherlands
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Novartis Investigative Site
Oslo, 0424, Norway
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Novartis Investigative Site
Esplugues, Barcelona, 08950, Spain
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Novartis Investigative Site
Gothenburg, SE 416 85, Sweden
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Novartis Investigative Site
London, NW1 2BU, United Kingdom
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Novartis Investigative Site
London, WC1N 3JH, United Kingdom
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Oregon Health and Science University
Portland, Oregon, 97239-3098, United States
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Phoenix Childrens Hospital
Phoenix, Arizona, 85016, United States
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Prinses Maxima Centrum voor Kinderoncologie
Utrecht, CS, 3584, Netherlands
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Rady Children s Hospital
San Diego, California, 92123, United States
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Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
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Stanford University Medical Center
Stanford, California, 94304, United States
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Texas Childrens Cancer and Hematology Center
Houston, Texas, 77030, United States
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The Childrens Hosp of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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UCSF Medical Center
San Francisco, California, 94143, United States
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Univ of Texas Southwest Med Center
Dallas, Texas, 75390-9034, United States
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University of Utah Clinical Trials Office
Salt Lake City, Utah, 84108, United States
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University of Wisconsin Hospital and Clinics Pharmacy/Drug Shipping Address
Madison, Wisconsin, 53792, United States
Conditions
Explore the condition pages connected to this study.