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Scientists hunt for tinnitus fingerprint in the brain

NCT ID NCT06520865

Diagnosis Sponsor: University of Regensburg Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked for a measurable brain signal (biomarker) that could objectively diagnose chronic tinnitus. Researchers used EEG to record brain activity in 560 adults—some with constant tinnitus and some without. The goal is to replace trial-and-error diagnosis with a personalized, data-driven tool that is easy to use in clinics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

560 people

The number who actually took part.

Started

Aug 2024

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who have been diagnosed with chronic tinnitus (for at least 6 months) and control subjects who have never had (except short-term) tinnitus.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: (1) for tinnitus cases: a diagnosis of chronic and constant tinnitus (for at least 6 months based on history) * (2) for controls: never experienced tinnitus * (3) age 18 -70; * (4) ability to understand and consent to the research; * (5) ability to participate (hearing ability); * (6) MoCa Test ≥ 26; * (7) hyperacusis questionnaire score \< 27; Exclusion Criteria: * (1) objective tinnitus; heartbeat-synchronous tinnitus as primary complaint; * (2) otosclerosis; acoustic neuroma or other relevant ear disorders with fluctuating hearing; * (3) acute ear nose and throat infections (acute otitis media, otitis externa, acute sinusitis); * (4) Meniere's disease or similar syndromes; * (5) vestibular migraine; * (6) serious internal, neurological or psychiatric conditions; * (7) epilepsy or other CNS disorders (brain tumor, encephalitis); * (8) clinically relevant drug, medication or alcohol abuse up to 12 weeks before study start; * (9) change in anti-depressants/drugs ≤ 2 weeks * (10) missing written informed consent * (11) severe hearing loss - inability to communicate properly in the course of the study; * (12) one deaf ear;

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Conditions

The condition(s) this trial relates to.

tinnitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tinnitus

Contacts and locations

Locations

  • Brai3n - Research center for Advanced, International, Innovative and Interdisciplinary Neuromodulation

    Ghent, 9000, Belgium

  • Center of Neuromodulation - Psychiatry und Psychotherapie der Universität Regensburg am Bezirksklinikum

    Regensburg, Bavaria, 93053, Germany

  • OST - Eastern Switzerland University of Applied Sciences

    Sankt Gallen, 9000, Switzerland

  • Trinity College Dublin

    Dublin, Ireland

  • University of Illinois

    Champaign, Illinois, 61820, United States

  • University of Texas

    Austin, Texas, 78712, United States

  • University of Tuebingen

    Tübingen, Baden-Wurttemberg, 72074, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.