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Could a common eye drop gel speed up wound healing?

NCT ID NCT03452072

Symptom relief Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether applying timolol gel (a drug usually used for glaucoma) to small surgical wounds after skin cancer removal helps them heal faster and look better. Researchers compared timolol gel to plain Vaseline in 87 adults with wounds up to 1.5 cm. The main goal was to see if more wounds were fully healed by 30 days with timolol, and to check for any side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
timolol gel
What this could lead to
If it works, this could offer a simple, low-cost way to speed up healing of small surgical wounds and improve scar appearance.
What could go wrong
This is a small, early-phase study with only 87 participants. The effect may be modest, and timolol can cause side effects like skin irritation or, rarely, heart or lung issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2/3

Runs two stages together: whether the treatment works, then large-scale confirmation.

Participants

87 people

The number who actually took part.

Started

Aug 2018

Finished

Jun 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age greater than 18 years 2. Open surgical wound ≤1.5cm 3. No hypersensitivity with use of 0.25% timolol gel Exclusion Criteria: 1. Age less than 18 years of age 2. Open surgical wound \>1.5cm 3. Pregnant women 4. Use of systemic retinoids within 1 month 5. Any hypersensitivity with use of 0.25% timolol gel

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Conditions

The condition(s) this trial relates to.

injury skin cancer Surgical Wound

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Surgical wound Wound heal Wound of skin Wound open

Contacts and locations

Locations

  • Mohs and Dermatologic Surgery Center, Brigham and Women's Hospital

    Boston, Massachusetts, 02130, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.