Heart attack timing trial: quicker scans may save lives in heart failure patients
NCT ID NCT07002164
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether doing a coronary angiogram (a special X-ray of the heart arteries) within 2 hours of diagnosis is better than waiting until the patient's heart failure symptoms improve. The study includes 780 adults with a type of heart attack called NSTEMI who also have new or worsening heart failure. The goal is to see if immediate imaging reduces the chance of death, another heart attack, or heart failure hospitalization over the next year.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Coronary angiography (a procedure to look at heart arteries using dye and X-rays)
- What this could lead to
- If it works, this could show that doing angiography within 2 hours reduces the risk of death, another heart attack, or heart failure hospitalization compared to waiting until the patient stabilizes.
- What could go wrong
- This is a single trial with 780 participants, so results may not apply to everyone. The study is open-label, meaning doctors and patients know which group they are in, which can bias results. There is also a risk that immediate angiography could cause complications in unstable patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 780 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Apr 2032
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥19 years * Non-ST-segment elevation myocardial infarction * New-onset or worsening of dyspnea (New York Heart Association class ≥2) * Pulmonary congestion * Patient's or guardian's consent after understanding the study Exclusion Criteria: * Cardiogenic shock at initial presentation * ST-segment elevation myocardial infarction * ST-segment elevation ≥0.1 mV in at least 2 contiguous leads, or * New onset left bundle branch block * Posterior wall myocardial infarction * Refractory angina * Life threatening ventricular arrhythmias * Life expectancy \<1 year * Apparently non-ischemic cause of HF * Pregnancy and lactation * History of coronary artery bypass grafting (CABG), or planned CABG * Patient's refusal to participate in study
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
19 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Asan Medical Center
RECRUITINGSeoul, South Korea
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Chonnam National University Hospital
RECRUITINGGwangju, South Korea
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Chungnam National University Hospital
RECRUITINGDaejeon, South Korea
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Dong-A University Hospital
NOT_YET_RECRUITINGPusan, South Korea
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Gwangju Veterans Hospital
RECRUITINGGwangju, South Korea
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Gyeongsang National University Changwon Hospital
RECRUITINGChangwon, South Korea
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Gyeongsang National University Hospital
RECRUITINGJinju, South Korea
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Jeonbuk National University Hospital
RECRUITINGJeonju, South Korea
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Kangbuk Samsung Medical Center
WITHDRAWNSeoul, South Korea
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Keimyung University Dongsan Hospital
RECRUITINGDaegu, South Korea
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Koera University Guro Hospital
NOT_YET_RECRUITINGSeoul, South Korea
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Korea University Anam Hospital
RECRUITINGSeoul, South Korea
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Kwangju Christian Hospital
NOT_YET_RECRUITINGGwangju, South Korea
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Kyungpook National University Hospital
NOT_YET_RECRUITINGDaegu, South Korea
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Samsung Medical Center
RECRUITINGSeoul, South Korea
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Seoul National University Bundang Hospital
NOT_YET_RECRUITINGSeongnam, South Korea
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Seoul National University Hospital
NOT_YET_RECRUITINGSeoul, South Korea
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St. Carollo General Hospital
RECRUITINGSuncheon, South Korea
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Yeongnam University Medical Center
RECRUITINGDaegu, South Korea
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Yonsei University, Wonju Severance Christian Hospital
RECRUITINGWŏnju, South Korea
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Which SGLT2 inhibitor wins? trial pits empagliflozin against dapagliflozin
- Every minute counts: study tracks how delays shape heart attack survival
- Can daily mindful breathing ease heart failure symptoms?
- The heart rhythm threat hiding in heart attack wards
- Stick-On patch aims to catch dangerous heart decline sooner
- Can a smartphone app keep heart failure patients out of the hospital?