Timing your meals and light exposure may tame type 2 diabetes
NCT ID NCT04155619
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether eating all meals earlier in the day and getting bright light therapy at specific times can improve blood sugar control in adults with type 2 diabetes. Researchers measured blood sugar, insulin, and other health markers in 190 participants. The goal was to see if these simple daily habits could help manage diabetes and improve overall health.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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190 people
The number who actually took part.
- Started
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Apr 2021
- Finished
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Apr 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 30-80 years old * Have type 2 diabetes * HbA1c between 5.7 - 12.0% * On a stable dose of metformin, DPP-IV inhibitors, SGLT2 inhibitors, sulfonylureas, and/or GLP-1 receptor agonists for at least 6 weeks, or taking no diabetes medications * Wake up at a regular time between 5-9 am Exclusion Criteria: * On insulin or diabetes medication other than metformin, DPP-IV inhibitors, SGLT2 inhibitors, sulfonylureas, and/or GLP-1 receptor agonists * Have type 1 diabetes or was diagnosed with diabetes before age 18 * Moderate or severe retinopathy or other medical condition that may affect the ability to safely receive bright light therapy * A history of severe hypoglycemia * Change in the dosage of a chronic medication within the past month (need to wait at least 1 month prior to baseline visit) * Have a clinically significant laboratory abnormality (e.g., abnormal hemoglobin levels) * Severe gastrointestinal disease, major gastrointestinal surgery, or active gallstone disease * Cardiovascular, renal, cardiac, liver, lung, adrenal, or nervous system disease that is unstable or may compromise study validity * Evidence of cancer (other than non-melanoma skin cancer) within the last 5 years * Pregnant or breastfeeding * Current diagnosis of a major psychiatric condition that would impair study participation * Diagnosed sleep disorder or circadian disorder that is not stabilized (sleep apnea is allowed). Those with narcolepsy will not be included. * Major changes in health or medical history in the last 3 months that could affect data validity per judgement of the study physician * Spend an average of more than 1.5 hours/day outdoors * Perform overnight shift work more than 1 day/week on average * Regularly eat within a less than a 10-hour period daily * Regularly finish eating dinner before 6:30 pm * Lost or gained more than 8 lbs within the last 2 months and weight needs to be stable for a minimum of 4 weeks before baseline testing * Traveled more than two times zones away in the two months prior to enrolling in the trial or will travel more than two time zones away during the 16-week study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Alabama at Birmingham; Birmingham Veterans Affairs Medical Center
Birmingham, Alabama, 35294, United States
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