Can intermittent fasting help paralyzed veterans lose weight?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Veteran * A member of the Spinal Cord Injury/Disorder (SCI/D) registry through the Syracuse VA, including both hub and spoke sites * A qualifying diagnosis of SCI within the SCI/D registry * Neurologic level of injury from T1 to S5, based on most recent Status Update or American Spinal Injury Association Impairment Scale (ASIA) examination, or a diagnosis of a hereditary form of paraplegia (such as familial spastic paraplegia or hereditary spastic paraplegia) * ASIA Impairment Scale grade A-D * Chronic SCI (\> 1 year from date of SCI or diagnosis of SCI) * BMI \> 22 - the BMI used to diagnose obesity in individuals with SCI * Mean eating window of at least 10 hours per day Exclusion Criteria: * Females who are pregnant (tested via urinary human chorionic gonadotropin (hCG)), planning to become pregnant in the next 6 months, or breast-feeding * A member of the SCI/D registry through the Syracuse VA, with a qualifying diagnosis of MS or ALS * Diagnosis of heart failure * Diagnosis of diabetes mellitus, type 1 * Diagnosis of diabetes mellitus, type 2, and on insulin or other antidiabetic agent with high incidence of hypoglycemia o Of note, antidiabetic agents with low incidence of hypoglycemia are: metformin, Glucagon-like peptide-1 (GLP-1) receptor agonists, Sodium-glucose cotransporter-2 (SGLT2) inhibitors, Dipeptidyl peptidase 4 (DPP-4) inhibitors, alpha glucosidase inhibitors, thiazolidinediones (as discussed with VA pharmacist) * Diagnosis of End Stage Renal Disease * Diagnosis of dementia * Diagnosis of orthostatic hypotension and prescribed midodrine or fludrocortisone * History of syncopal episode in the month prior to the study * History of significant weight loss (\> 10% body weight) in the month prior to the study * History of eating disorders (e.g., anorexia or bulimia) within the last five years, or clearance from a mental health provider * History of active suicidal ideation in the last six months, or clearance from a mental health provider * Currently prescribed weight loss medication (e.g., liraglutide) * Currently prescribed corticosteroids * Current acute medical issues including cancer, sepsis, advanced liver failure, porphyria, or uncontrolled hyperthyroidism