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Can a 10-Hour eating window and lighter foods beat insulin resistance?

NCT ID NCT06259435

Disease control Sponsor: Pennington Biomedical Research Center Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether eating only between certain hours (a 10-hour window each day) and choosing foods that are less calorie-dense (fewer calories per bite) can help older adults with obesity and insulin resistance. Forty participants followed this eating pattern, and researchers measured changes in insulin resistance, body weight, and other health markers. The goal was to see if this approach could improve how the body handles sugar and help with weight control.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

May 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Body mass index (BMI) ≥ 30kg/m2. 2. Mini-Mental State Examination (MMSE) \> 25 3. Geriatric Depression Scale-15 (GDS-15) \< 9 4. Homeostatic model assessment of insulin resistance (HOMA-IR) ≥ 3. Exclusion Criteria: 1. Diagnosis of Type 2 diabetes received more than five years ago 2. Diagnosis of type 1 diabetes 3. Evidence of clinically significant renal dysfunction or disease 4. History of malignancy during the past five years 5. Being treated with systemic steroids, olanzapine, or clozapine 6. Being treated with prescription medications for obesity 7. Being treated with thiazolidinediones, glucagon-like-receptor agonists, Dipeptidyl Peptidase IV inhibitors, and insulin 8. Weight change \> 3 kg in the preceding three months 9. Any disease or condition that precludes testing of the study outcomes or makes it unsafe to consume the foods being tested in the study, or subjects are otherwise deemed to be unsuitable for participation in the study (determined by the investigative team)

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Conditions

The condition(s) this trial relates to.

Body Weight Insulin Resistance obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Body weight Insulin resistance

Contacts and locations

Locations

  • Pennington Biomedical Research Center

    Baton Rouge, Louisiana, 70808, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.