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Promising MDS drug trial stopped early – what happened?

NCT ID NCT04823624

First seen Oct 31, 2025 · Last updated May 22, 2026 · Updated 30 times

Summary

This study tested a drug called MBG453 in 10 people with lower-risk myelodysplastic syndromes (MDS), a bone marrow disorder. The goal was to see if the drug could improve blood cell counts and reduce the need for blood transfusions. The trial was terminated early, so results are limited.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02215, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.