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Ancient mushroom put to the test for athletic edge

NCT ID NCT07756788

Disease control Sponsor: Nexus Wise Sdn Bhd Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This trial tests whether a traditional Southeast Asian mushroom, tiger milk mushroom, can improve physical performance and recovery in active adults. Over 12 weeks, participants take either the mushroom supplement or a placebo, and researchers measure changes in aerobic capacity, muscle strength, perceived exertion, and blood markers of recovery and inflammation. The goal is to see if this natural supplement can support exercise capacity and overall wellbeing.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Tiger Milk Mushroom (Lignosus rhinocerus) extract, taken as a 300 mg capsule twice daily for 12 weeks
What this could lead to
If effective, this supplement could offer a natural way to enhance aerobic capacity, muscle strength, and recovery in physically active people.
What could go wrong
This is a small, early-stage trial, and results may not apply broadly. The supplement's effects on performance and recovery are not yet proven, and individual responses may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

65 people

The number who actually took part.

Started

Jan 2025

Finished

May 2026

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female adults aged 18 years and above * Physically active individuals who regularly participate in physical exercise or fitness-related activities * Generally healthy based on self-reported medical history * Willing and able to comply with all study procedures and scheduled visits * Willing to provide written informed consent Exclusion Criteria: * Current cigarette smokers * Users of psychoactive substances * Individuals consuming more than 600 mL of caffeinated beverages per day * Diagnosis of chronic metabolic diseases, including but not limited to type 2 diabetes mellitus or cardiovascular disease * Diagnosis of autoimmune disease * Pregnant or lactating women * Known allergy or hypersensitivity to mushroom-derived products * Current use of supplements or medications that may influence physical performance, inflammatory status, or immune function, as determined by the investigator * Participation in another clinical trial within 30 days prior to enrollment * Any medical condition that, in the opinion of the investigator, may interfere with study participation or interpretation of the study results

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Exercise capacity Physical fitness Physical performances

Contacts and locations

Locations

  • UCSI University

    Cheras, Kuala Lumpur, 56000, Malaysia

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