New sound test could spot thyroid cancer without needles
NCT ID NCT06207188
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new imaging method called vibro-acoustography (VA) to find and tell apart harmless and cancerous thyroid nodules. Researchers at Mayo Clinic will compare VA images to standard ultrasound in 650 people aged 8 and older who are at risk for thyroid cancer. The goal is to see if VA can accurately locate nodules and distinguish malignant from benign ones, potentially reducing unnecessary biopsies.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 650 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2009
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patient volunteers ages 8 and up who are suspicious for thyroid cancer or a group of patients who have palpable and sonographically detectable lymph nodes or nonthyroidal neck masses or who were previously diagnosed with thyroid cancer and treated with thyroidectomy and recently diagnosed as having recurrence nodes on thyroid bed or on their neck.
- Ages
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8 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * \* Male and female patient volunteers ages 8 and up who are suspicious for thyroid cancer * Patients who have palpable and sonographically detectable lymph nodes or nonthyroidal neck masses and are referred to Radiology Department or Endocrinology for fine-needle aspiration biopsy (FNAB) * Patients 18 and up who were previously diagnosed with thyroid cancer and treated with thyroidectomy and recently diagnosed as having recurrence nodes on thyroid bed or on their neck Exclusion Criteria: * Because thyroid cancer is rare under the age of 8 years, children younger than this age are excluded from the study * Having FNAB or surgical biopsy on thyroid in less than two weeks for thyroid nodule detection group * Having FNAB or surgical biopsy on cervical lymph nodes or non- thyroidal masses for this group of patients
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
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Genom att skicka in godkänner du våra Användarvillkor
Study contacts
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Contact
Email: •••••@•••••
Locations
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Mayo Clinic in Arizona
RECRUITINGScottsdale, Arizona, 85259, United States
Contact Email: •••••@•••••
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Mayo Clinic in Florida
RECRUITINGJacksonville, Florida, 32224-9980, United States
Contact Email: •••••@•••••
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Mayo Clinic in Rochester
RECRUITINGRochester, Minnesota, 55905, United States
Contact Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Mapping how thyroid tumors spread and what surgery leaves behind
- Can a video keep thyroid cancer patients on track after surgery?
- Can doctors safely watch small thyroid cancers instead of removing them?
- Can heat replace the scalpel for small thyroid tumors?
- Thyroid surgery under the microscope: what 3,000 real operations reveal