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Thumb bone index may predict scoliosis growth spurts

NCT ID NCT03904914

Knowledge-focused Sponsor: Chinese University of Hong Kong Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new thumb bone staging system (TOCI) to predict skeletal maturity and curve progression in 1,500 teens with idiopathic scoliosis. Researchers evaluated thumb X-rays to see if the simple index could replace complex methods like the Risser sign or Greulich-Pyle atlas. The goal is to help doctors decide on bracing and treatment more easily in clinic.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a quick, simple tool to predict growth spurts and scoliosis worsening, helping decide when to brace or treat.
What could go wrong
This is an observational study, not a treatment trial. The new index may not be more accurate than existing methods, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 1,500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2016

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Scoliosis patients will be recruited from a specialized scoliosis clinic in Prince of Wales hospital visiting the clinic.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female * Pre-menarche * Confirmed diagnosis of idiopathic scoliosis * No evidence of neurological abnormality * No abnormalities of maturation * Risser sign of zero in spinal radiograph and open physis in hand radiograph Exclusion Criteria: * Patients with diagnosis of non-idiopathic scoliosis, e.g. congenital, neuromuscular , syndromal cause of scoliosis * Patients with maturation abnormality (either precocious puberty or developmental delay) * Abnormalities of the head or neck that would change height measurements * Previous history of spinal fusion operation performed

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Conditions

The condition(s) this trial relates to.

adolescent idiopathic scoliosis Bone Diseases, Developmental bone disorder scoliosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone diseases Bone growth abnormal Scoliosis; adolescence

Contacts and locations

Locations

  • Prince of Wales Hospital

    Shatin, Hong Kong

More trials for these conditions

Other studies related to the condition(s) this trial covers.