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3D ultrasound could spot hidden clot risks in aneurysms

NCT ID NCT05841524

Knowledge-focused Sponsor: St. Olavs Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study explores whether a special 3D ultrasound technique, called vector flow imaging, can predict where blood clots form inside abdominal aortic aneurysms. Researchers will scan 14 people with small aneurysms (under 5.5 cm), half with existing clots and half without. They will also test whether injecting contrast microbubbles improves the image quality. The goal is to see if this non-invasive method can reliably measure blood flow patterns linked to clot formation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this imaging technique could help predict which aneurysms are at risk of forming dangerous blood clots, guiding earlier treatment.
What could go wrong
This is a very small feasibility study with only 14 participants, so results may not apply broadly. The technique is still experimental and not ready for routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

14 people

The number who actually took part.

Started

Apr 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients diagnosed with an AAA. Both with and without intraluminal thrombus present.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with AAA * AAA diameter below treatment threshold of 5.5 cm Exclusion Criteria: * Hypersensitivity to the active substance(s) or any of the excipients in Sonovue * Right-to-left cardiac shunt * Severe pulmonary hypertension (pulmonary artery pressure \> 90mmHg) * Uncontrolled systemic hypertension * Severe pulmonary disease (e.g. COPD GOLD 3 or 4, adult respiratory distress syndrome) * Clinically unstable cardiac disease (recent, \< 3 months, or ongoing myocardial infarction, unstable angina at rest, recent percutaneous coronary intervention, clinically worsening cardiac symptoms, severe cardiac arrhythmia's, endocarditis, etc.) * Prosthetic valves * Loss of renal function (GFR \< 31 ml/min), end-stage renal disease * End-stage liver disease * Sepsis

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Conditions

The condition(s) this trial relates to.

abdominal aortic aneurysm thrombotic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal aneurysm Thrombus

Contacts and locations

Locations

  • St. Olavs hospital, Trondheim University Hospital

    Trondheim, Trøndelag, 3250, Norway

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