Can a Clot-Sucking catheter save the gut in a medical emergency?
NCT ID NCT07741318
First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time
Summary
This trial is testing whether a catheter that suctions out blood clots can restore blood flow to the intestine in people with acute mesenteric ischemia, a life-threatening blockage of the artery feeding the gut. Participants will undergo thrombus aspiration, and if needed, laparoscopic surgery to check the bowel and remove any dead tissue. The study will track survival and complications over a year to see if this approach is safe and effective.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- thrombus aspiration-based endovascular therapy using a peripheral thrombus aspiration catheter, with laparoscopic surgery when needed
- What this could lead to
- If effective, this approach could offer a less invasive way to restore blood flow to the intestine, potentially reducing the need for open surgery and improving survival in a life-threatening emergency.
- What could go wrong
- This is a single-arm study with no comparison group, so benefits may be uncertain. The procedure carries risks like bleeding, vessel damage, or incomplete clot removal, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 76 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Sep 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years, with no restriction on sex. * Acute mesenteric ischemia (AMI) caused by superior mesenteric artery (SMA) thrombosis or thromboembolism. * The participant or legally authorized representative can provide written informed consent, and the participant is willing and able to comply with the follow-up requirements. Exclusion Criteria: * Presence of unfavorable vascular anatomical factors, including severe arterial tortuosity, concomitant aortic disease, superior mesenteric artery aneurysm, or other anatomical conditions considered unsuitable for endovascular intervention. * Acute major myocardial infarction, extensive cerebral infarction, or severe heart failure within 1 month before enrollment. * Patients unable to receive regular anticoagulation, thrombolytic therapy, or antiplatelet therapy due to gastrointestinal bleeding, severe allergic reactions, coagulation disorders, severe hepatic or renal dysfunction, or other contraindications. * Patients unable to undergo endovascular procedures due to severe contrast media allergy, severe renal insufficiency, or other contraindications. * History of previous superior mesenteric artery (SMA) thromboembolism or thrombosis. * Patients with confirmed intestinal necrosis before the procedure who underwent direct exploratory laparotomy without receiving endovascular intervention. * Pregnant or breastfeeding women. * Patients currently participating in other interventional device or drug clinical trials. * Any other conditions deemed inappropriate for enrollment by the investigator.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Intestinal Stroke Center of Beijing Tsinghua Changgung Hospital
Beijing, 102200, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.