Can we predict dangerous blood clots in lung cancer immunotherapy patients?
NCT ID NCT06950697
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how often lung cancer patients on immune checkpoint inhibitors develop blood clots (in veins or arteries) and what factors increase that risk. Researchers will follow 2,400 adults with lung cancer who are starting immunotherapy, comparing those who get clots with those who don't. The goal is to build a simple risk-prediction tool doctors can use to prevent clots and improve treatment safety.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 2,400 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2019
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with histopathologically confirmed lung cancer who were treated with immune checkpoint inhibitors between January 1, 2019, and December 31, 2026.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years * Histopathologically confirmed lung cancer diagnosis at enrollment * Received at least one dose of a China-approved lung cancer immune checkpoint inhibitor * Signed informed consent form Exclusion Criteria: * Presence of two or more primary cancers * Missing data for key variables * Inability to comply with follow-up requirements * Presence of VTE/ATE at the time of ICI initiation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
5 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beijing Chaoyang Hospital, Capital Medical University
RECRUITINGBeijing, China
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Beijing Luhe Hospital, Capital Medical University
RECRUITINGBeijing, China
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China-japan Friendship Hospital
RECRUITINGBeijing, China
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The First Affiliated Hospital of Zhengzhou University
RECRUITINGZhengzhou, Henan, China
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The Fourth Hospital of Inner Mongolia Autonomous Region
RECRUITINGHohhot, Inner Mongolia, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a gentler blood thinner shield cancer patients from new clots?
- Can AI make lung cancer scans easier to read?
- Two-Drug combo targets Treatment-Resistant lung cancer
- Can an Anti-Fibrotic drug shield lungs from radiation after immunotherapy?
- App aims to catch a hidden radiotherapy side effect