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Throat cancer breakthrough: less treatment may be just as effective

NCT ID NCT05119036

First seen May 23, 2026 · Last updated Jun 18, 2026 · Updated 5 times

Summary

This study looks at whether reducing or stopping additional treatments (like chemo or radiation) after surgery for HPV-positive throat cancer can still prevent the cancer from coming back. The goal is to maintain good outcomes while avoiding harsh long-term side effects. About 83 adults with HPV-positive oropharyngeal cancer are being followed to see how well this lighter approach works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • IU Health Joe and Shelly Schwarz Cancer Center

    Carmel, Indiana, 46032, United States

  • Indiana University Melvin and Bren Simon Comprehensive Cancer Center

    Indianapolis, Indiana, 46202, United States

Conditions

The condition(s) this trial relates to.

human papillomavirus-related squamous cell carcinoma oropharynx squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.