New study tracks 1,500 transplant patients to unlock secrets of a devastating complication
NCT ID NCT05919511
First seen Jun 27, 2026 · Last updated Aug 26, 2026 · Updated 2 times
Summary
This study follows 1,500 adults who recently had a stem cell transplant and are at risk for chronic Graft-Versus-Host Disease (cGVHD), a condition where donor cells attack the recipient's body. Researchers will collect data on how often cGVHD occurs, how severe it is, and what healthcare resources are needed to manage it. The goal is to better understand the disease and improve future care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2023
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants greater than or equal to 18 years of age who have had Allogenic SCT 90 to 180 days prior to enrollment
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years inclusive at the time of signing the ICF * Allogeneic SCT 90 to 180 days prior to enrollment * Able to comprehend and willing to provide informed consent * Willing and able to complete participant-assessment questionnaires either alone or with minimal assistance from a caregiver and/or trained site personnel Exclusion Criteria: * There are no exclusion criteria for this study
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CGVHD are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
31 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
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Contact
Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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AdventHealth Orlando
RECRUITINGOrlando, Florida, 32803, United States
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City of Hope
RECRUITINGDuarte, California, 91010, United States
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Corewell Health
RECRUITINGGrand Rapids, Michigan, 49503, United States
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Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
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Fred Hutchinson Cancer Research Center
RECRUITINGSeattle, Washington, 98109, United States
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Geisinger Health Systems
RECRUITINGDanville, Pennsylvania, 17822, United States
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Georgia Cancer Center
RECRUITINGAugusta, Georgia, 30912, United States
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Levine Cancer Institute
RECRUITINGCharlotte, North Carolina, 28204, United States
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Loyola University Medical Center
RECRUITINGMaywood, Illinois, 60153, United States
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Massachusetts Cancer Research Center
RECRUITINGBoston, Massachusetts, 02114, United States
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Mayo Clinic Arizona
RECRUITINGPhoenix, Arizona, 85054, United States
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Mayo Clinic Jacksonville
RECRUITINGJacksonville, Florida, 32224, United States
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Mayo Clinic Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10021, United States
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Moffit Cancer Center
RECRUITINGOrlando, Florida, 33612, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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Oregon Health Sciences University
RECRUITINGPortland, Oregon, 97239, United States
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Rush University Medical Group
RECRUITINGChicago, Illinois, 60612, United States
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Rutgers Cancer Institute of New Jersey
RECRUITINGNew Brunswick, New Jersey, 08602, United States
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Texas Oncology-Baylor Charles A. Sammons Cancer Center
RECRUITINGDallas, Texas, 75246, United States
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The Ohio State University
RECRUITINGColumbus, Ohio, 43201, United States
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The University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
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The University of Kansas Clinical Research Center
RECRUITINGFairway, Kansas, 66205, United States
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Tulane Cancer Center
COMPLETEDNew Orleans, Louisiana, 70112, United States
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USC Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
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University of Alabama Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
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University of Colorado
RECRUITINGAurora, Colorado, 80309, United States
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University of Maryland Medical Center
RECRUITINGBaltimore, Maryland, 21201, United States
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University of North Carolina at Chapel Hill
RECRUITINGChapel Hill, North Carolina, 27514, United States
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University of Utah, Huntsman Cancer Institute
RECRUITINGSalt Lake City, Utah, 84112, United States
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37212, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Which drug tames liver Graft-Versus-Host disease better? a trial puts two to the test
- Can a skin biopsy reveal how axatilimab fights scarring in chronic GVHD?
- New antibody cocktail targets stubborn liver disease after stem cell transplants
- New drug combo aims to tame transplant complication
- Arthritis drug repurposed to fight stem cell transplant complication
- New combo therapy aims to tame chronic GVHD